磁共振兼容型大鼠小鼠監(jiān)護儀,是starr公司為MRI磁共振環(huán)境下大鼠、小鼠的生命體征檢測專門開發(fā)的設(shè)備。

可以在MRI環(huán)境下測量小動物(幼鼠小鼠大鼠豚鼠兔等)的血氧飽和度脈搏頻率呼吸頻率脈搏幅度呼吸幅度；

所有測量都是通過一個的感應(yīng)器；

主要功能

· 無磁探頭適合核磁環(huán)境中監(jiān)測動物的生命體征；

· 監(jiān)測和記錄多種心肺功能參數(shù)動脈血氧飽和度脈搏脈搏幅度呼吸頻率呼吸幅度

· 可輸出模擬數(shù)據(jù)

所有測量都是通過一個的感應(yīng)器完成準(zhǔn)確、方便、高效。

型號MouseOx     正在對麻醉狀態(tài)下的小鼠進行測試

有多種探頭可供選擇

· 根據(jù)實驗需求可選擇大鼠型探頭、小鼠型探頭；

· 根據(jù)動物狀態(tài)可選擇清醒活動狀態(tài)連續(xù)測量和麻醉（或手術(shù)）狀態(tài)測量探頭；

· 根據(jù)動物數(shù)量有多通道適配器可供選擇同時檢測多只動物的生命體征；

· 根據(jù)使用環(huán)境可選擇核磁環(huán)境適用的無磁探頭；

經(jīng)過驗證的準(zhǔn)確度:

使用有創(chuàng)血氣采樣測量結(jié)果與 MouseOx 測量結(jié)果的比較 對比表明 兩者具有很好的線性關(guān)系。

脈搏、血氧、呼吸等心肺監(jiān)測參數(shù):

· 脈波頻率在90到900BPM范圍內(nèi)監(jiān)測 (每分鐘心跳, Beat per minutes, BPM)

· 血氧飽和度監(jiān)測范圍0% 到99% 動脈血氧飽和度；

· 血氧飽和度監(jiān)測誤差<1.5% 橫跨整個監(jiān)測范圍；

· 血氧飽和度監(jiān)測反應(yīng)時間實時報告動脈血氧飽和度, 在每次心跳以后0.72秒屏幕刷新；

· 呼吸頻率監(jiān)測范圍每分鐘 25到450 次；

· 監(jiān)測反應(yīng)時間呼吸率每1.7秒向用戶報告, 移動報告的值是10次呼吸的的平均數(shù)；

· 傷監(jiān)測脈搏充盈度以估量血流量的變化；

· 脈搏監(jiān)測范圍內(nèi)徑0到800微米的徽小血管；

· 監(jiān)測誤差< 2.4%橫跨整個監(jiān)測范圍；

· 監(jiān)測反應(yīng)時間脈搏充盈度實時向用戶報告, 在每次心跳以后,0.72秒屏幕刷新刷新屏幕顯示被測量的所有脈搏充盈度；

· 傷監(jiān)測動物呼吸幅度的變化；

· 呼吸幅度監(jiān)測范圍每分鐘25到450次；

· 呼吸幅度監(jiān)測反應(yīng)時間呼吸率每1.7秒向用戶報告, 移動報告的值是10次呼吸的的平均數(shù)；

血氧呼吸數(shù)據(jù)采集器

8通道數(shù)據(jù)采集器

可對1-8只老鼠進行脈搏、血氧、呼吸的數(shù)據(jù)測量

模擬信號輸出模塊

搭配模擬信號輸出模塊實時輸出模擬心博

多鐘測試探頭可選

根據(jù)需要可選擇老鼠清醒狀態(tài)下使用的頸部探頭麻醉狀態(tài)下使用的足部探頭和大腿探頭

測量軟件

實時顯示監(jiān)測數(shù)據(jù)具有診斷模式具備報價功能數(shù)據(jù)可儲存為Text貨Windaq格式

設(shè)備正在對清醒活動狀態(tài)的大鼠進行長時間、持續(xù)的數(shù)據(jù)采集

玉研儀器是美國STARR公司的中國代理美國Starr公司的Mouseox是專門應(yīng)用于小鼠和大鼠的監(jiān)護儀可以測量脈搏血氧呼吸心率脈搏幅度呼吸幅度體溫等參數(shù)。詳情請!

· Calibration and Validation of the MouseOx® Small-Animal Pulse Oximeter
Kingman P. Strohl* MD, David Baekey* PhD, Susan Dase** MS and Bernie Hete** PhD.
*Department of Pulmonary and Critical Care Medicine, Case Western Reserve University
**Department of Engineering, STARR Life Sciences Corp.

· Transfusion-related Acute Lung Injury
Chelsea A. Sheppard, MDa, Lennart E. Lo¨ gdberg, MD, PhDa, James C. Zimring, MD, PhDa, Christopher D. Hillyer, MDb,
aDepartment of Pathology and Laboratory Medicine, Room D-655, Emory University School of Medicine, 1364 Clifton Road, NE, Atlanta, GA 30322, USA
bDepartment of Pathology and Laboratory Medicine, Transfusion Medicine Program, Room D-655, Emory University Hospital, 1364 Clifton Road, NE, Atlanta, GA 30322, USAHEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA

· Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
Adam T. Boutin,1 Alexander Weidemann,1 Zhenxing Fu,5 Lernik Mesropian,1
Katarina Gradin,2 Colin Jamora,1 Michael Wiesener,3 Kai-Uwe Eckardt,3 Cameron J. Koch,4 Lesley G. Ellies,5
Gabriel Haddad,5 Volker H. Haase,4 M. Celeste Simon,4 Lorenz Poellinger,2 Frank L. Powell,5 ａnd Randall S. Johnson1
1Molecular Biology Section, Division of Biological Sciences, UC San Diego, La Jolla, CA 92093, USA
2Karolinska Institute, Stockholm S-17177, Sweden
3University of Erlangen, Erlangen D-91054, Germany
4University of Pennsylvania Medical School, Philadelphia, PA 19104, USA
5Departments of Medicine, Pediatrics, and Pathology, UC San Diego School of Medicine, La Jolla 92093 CA, USA

· Age-related cardiac muscle sarcopeniaCombining experimental
and mathematical modeling to identify mechanisms
Jing Lin a,b, Elizabeth F. Lopez a,c, Yufang Jin f, Holly Van Remmen d,e, Terry Bauch a, Hai-Chao Han g, Merry L. Lindsey a,b,d,e
aDivision of Cardiology, Department of Medicine, The University of Texas Health Science Center at San Antonio (UTHSCSA),
7703 Floyd Curl Dr., MC-7872, San Antonio, TX 78229, USA
bThe Janey Briscoe Center of Excellence in Cardiovascular Research, UTHSCSA, USA
cJohn Jay Science and Engineering Academy, UTHSCSA, USA
dThe Barshop Institute for Longevity and Aging Studies, UTHSCSA, USA
eDepartment of Cellular and Structural Biology, UTHSCSA, USA
fDepartment of Electrical Engineering, UTSA, USA
gDepartment of Mechanical Engineering, UTSA, USA

· Post infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection
Ian C. Davis1, Eduardo R. Lazarowski2, Fu-Ping Chen3, Judy M. Hickman-Davis1, Wayne M. Sullender3,4, and Sadis Matalon1,4,5
1 Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
2 Department of Medicine, UNC, Chapel Hill, NC, USA
3 Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, USA
4 Department of Micrology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
5 Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, AL 35233, USA

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