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參考價(jià)	面議

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CAS號	7424-00-2	產(chǎn)地	進(jìn)口
規(guī)格	5g	級別	食品級

名稱：4-氯-DL-苯丙氨酸 Sigma
描述：4-氯-DL-苯丙氨酸（PCPA）是5-羥色胺（5-HT）合成的抑制劑。有助于改善肺組織炎癥，重塑肺動(dòng)脈。PCPA可降低色氨酸羥化酶1（TPH1）、基質(zhì)金屬蛋白酶（MMP）和促炎因子的表達(dá)色氨酸羥化酶抑制劑。

詳細(xì)介紹

4-氯-DL-苯丙氨酸 Sigma

Application

4-Chloro-DL-phenylalanine has been used:
• as tryptophan hydroxylase 1 (TPH1) inhibitor to treat kras⁺ male zebrafish^[2]
• to induce insomnia in rat models^[3]
• used to treat embryos to examine its effect on serotonin^[4]
• for the selection of Enterococcus faecalis transformants with pESentA32 plasmid^[5]
• to feed flies to explore serotonin effect^[6]

包裝

5, 25 g in poly bottle

Features and Benefits

該化合物也是Sigma藥理活性化合物庫（LOPAC^®¹²⁸⁰）的一部分，該化合物庫是一個(gè)具有生物學(xué)注釋的高品質(zhì)、可即時(shí)篩選化合物的集合。

性質(zhì)

Related Categories	Chemical Synthesis, Enzyme Inhibitors, Greener Alternative Products, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Re−engineered Products, Tryptophan Hydroxylase, 細(xì)胞信號轉(zhuǎn)導(dǎo)和神經(jīng)科學(xué), 細(xì)胞生物學(xué) Less...
Quality Level	100
greener alternative product characteristics	Waste Prevention Designing Safer Chemicals Reduce Derivatives Learn more about the Principles of Green Chemistry.
mp	>240 °C (dec.) (lit.)
greener alternative category	Re-engineered
storage temp.	room temp
SMILES string	NC(Cc1ccc(Cl)cc1)C(O)=O
InChI	1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChI key	NIGWMJHCCYYCSF-UHFFFAOYSA-N
Gene Information	human ... TPH1(7166), TPH2(121278)

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4-氯-DL-苯丙氨酸 Sigma

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