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LY2510924，LY2510924游離態(tài)，拮抗劑LY2510924，環(huán)肽，抑制劑
Product structure：

Product specifications：
1.CAS No：1088715-84-7
2.Molecular formula：C62H88N14O10
3.Molecular weight：1189.450
4.density：1.3±0.1 g/cm3
5.Packaging specification：1g、5g、10g, flexible packaging, including 100mg packaging and 500mg 1g and 5g large packaging
6.Dissolution conditions：Soluble in most organic solvents, such as DCM, DMF, DMSO, THF, etc., with good solubility in water
7.Stability：-1 year at 20 ° C, dry and dark.
Reaction characteristics：
LY2510924是一種有效的、選擇性的CXCR4拮抗劑，特異性地阻止SDF-1與CXCR4的結(jié)合，IC50為0.079 nM；抑制SDF-1誘導(dǎo)的GTP結(jié)合，Kb值為0.38 nM。
LY2510924抑制SDF-1誘導(dǎo)的細(xì)胞遷移，IC50為0.26 nM；并抑制SDF-1/CXCR4介導(dǎo)的胞內(nèi)信號(hào)。LY2510924沒(méi)有明顯的激動(dòng)活性。它對(duì)其他趨化因子受體如CCR1,CCR2,CXCR2和CXCRChemicalbook3在檢測(cè)濃度下沒(méi)有抑制活性，對(duì)5-羥色胺受體、多巴胺受體、opioidreceptors也沒(méi)有活性。
Matters for use：
It is sensitive to light and temperature. In order to use the reagent effectively, the material should always be kept in a low temperature dry condition, away from light, and avoid frequent thawing and freezing.
storage conditions:
Store at - 20 ℃ as much as possible. If conditions permit, the material can be treated under inert gas to obtain better stability of the reagent.
【 reagent related products】
N-cyclopropene-L-Lysine
Octaphenylcyclotetrasiloxane
cyclo(L-Pro-L-Tyr)，Maculosin
1,7-Dioxa-4,10-diazacyclododecane
Cyclo(L-Phe-trans-4-hydroxy-L-Pro)
Cyclo(L-Leu-trans-4-hydroxy-L-Pro)
(3-Azidobutyl)cyclohexane
(Azidomethyl)-cyclohexane
N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7
N-(m-PEG4)-N'-(4-hydroxycyclohexyl-1-amido-PEG4)-Cy5
3-(trifluoromethyl)cyclohexan-1-ol
(Cyclo(Glu22-Lys26),Leu27)-pTH (1-31) amide (human)
1,1,3,3,5,5-Hexamethyl Cyclotrisilazane
1,1,3,3,5,5,7,7-Octamethyl Cyclotetrasilazane
Tris(Cyclohexylamino)Methylsilane
以上編輯的試劑信息僅用于科學(xué)研究或者工業(yè)應(yīng)用等非醫(yī)療目的，非藥用，非食用。接受各種復(fù)雜定制服務(wù)，合成的Monodispersed PEGs除了有更多樣的基團(tuán)還可以提供各種不同數(shù)量的PEG的產(chǎn)品。

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