久久亚洲精品天码av,午夜福利屄插穴,午夜福利视频91,亚欧美爽爽爽爽爽,亚洲欧美日韩色色图片,青青操在线观看,精品天堂麻豆av,无码av东京热,婷婷成人亚洲少妇

行業(yè)產(chǎn)品

  • 行業(yè)產(chǎn)品

北京方程嘉鴻科技有限公司


當(dāng)前位置:北京方程嘉鴻科技有限公司>>細(xì)胞因子>>Recombinant PEDF貨號(hào):130-13 細(xì)胞因子

Recombinant PEDF貨號(hào):130-13 細(xì)胞因子

返回列表頁(yè)
參  考  價(jià)面議
具體成交價(jià)以合同協(xié)議為準(zhǔn)

產(chǎn)品型號(hào)

品       牌

廠商性質(zhì)生產(chǎn)商

所  在  地北京市

聯(lián)系方式:王杰查看聯(lián)系方式

更新時(shí)間:2016-02-12 18:19:06瀏覽次數(shù):10341次

聯(lián)系我時(shí),請(qǐng)告知來(lái)自 制藥網(wǎng)

產(chǎn)品簡(jiǎn)介

Recombinant PEDF 貨號(hào):130-13 細(xì)胞因子
細(xì)胞因子(cytokine,CK)是一類能在細(xì)胞間傳遞信息、具有免疫調(diào)節(jié)和效應(yīng)功能的蛋白質(zhì)或小分子多肽。
作用特點(diǎn):多效性、重疊性、協(xié)同性、拮抗性和雙重性。

詳細(xì)介紹

Recombinant PEDF 貨號(hào):130-13 細(xì)胞因子

 

胞因子受體存在著可溶性形式,掌握可溶性細(xì)胞因子受體產(chǎn)生的規(guī)律及其生理和病理意義,必將擴(kuò)展人們對(duì)細(xì)胞因子網(wǎng)絡(luò)作用的認(rèn)識(shí)。檢測(cè)細(xì)胞因子及其受體的水平已成為基礎(chǔ)和臨床免疫學(xué)研究中的一個(gè)重要的方面。Catalog Number:

 
Catalog Number:
130-13
Synonyms:
Pigment epithelium-derived factor, SerpinF1, EPC-1
Description:
PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body. A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. In addition, PEDF is able to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins. The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity (1) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. To date, PEDF-R is the only signaling receptor known to be used by a serpin family member. The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers. Recombinant PEDF is a 44.5 kDa non-glycosylated protein containing 400 amino acid residues. (1) Notari, I. et al. J Biol Chem., Vol. 281, 38022-38037.
AA Sequence:
MQNPASPPEE GSPDPDSTGA LVEEEDPFFK VPVNKLAAAV SNFGYDLYRV RSSMSPTTNV LLSPLSVATA LSALSLGAEQ RTESIIHRAL YYDLISSPDI HGTYKELLDT VTAPQKNLKS ASRIVFEKKL RIKSSFVAPL EKSYGTRPRV LTGNPRLDLQ EINNWVQAQM KGKLARSTKE IPDEISILLL GVAHFKGQWV TKFDSRKTSL EDFYLDEERT VRVPMMSDPK AVLRYGLDSD LSCKIAQLPL TGSMSIIFFL PLKVTQNLTL IEESLTSEFI HDIDRELKTV QAVLTVPKLK LSYEGEVTKS LQEMKLQSLF DSPDFSKITG KPIKLTQVEH RAGFEWNEDG AGTTPSPGLQ PAHLTFPLDY HLNQPFIFVL RDTDTGALLF IGKILDPRGP
Source:
E.coli
Purity:
Greater than 90% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Data Not Available.
 
 
 
 
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular Apoptosis Apoptosis
Cancer Cancer Neurobiology Neurobiology
 
 
Country of Origin:
USA


您感興趣的產(chǎn)品PRODUCTS YOU ARE INTERESTED IN

制藥網(wǎng) 設(shè)計(jì)制作,未經(jīng)允許翻錄必究 .? ? ? Copyright(C)?2021 http://m.jjhengye.com,All rights reserved.

以上信息由企業(yè)自行提供,信息內(nèi)容的真實(shí)性、準(zhǔn)確性和合法性由相關(guān)企業(yè)負(fù)責(zé),制藥網(wǎng)對(duì)此不承擔(dān)任何保證責(zé)任。 溫馨提示:為規(guī)避購(gòu)買風(fēng)險(xiǎn),建議您在購(gòu)買產(chǎn)品前務(wù)必確認(rèn)供應(yīng)商資質(zhì)及產(chǎn)品質(zhì)量。

會(huì)員登錄

×

請(qǐng)輸入賬號(hào)

請(qǐng)輸入密碼

=

請(qǐng)輸驗(yàn)證碼

收藏該商鋪

請(qǐng) 登錄 后再收藏

提示

您的留言已提交成功!我們將在第一時(shí)間回復(fù)您~
灵宝市| 仙游县| 丁青县| 孟村| 柳林县| 义马市| 临洮县| 林州市| 邵阳县| 六盘水市| 八宿县| 太白县| 武夷山市| 德州市| 成都市| 江达县| 西青区| 芒康县| 达孜县| 东乡县| 巨野县| 阳原县| 唐海县| 乡城县| 台北县| 普兰县| 哈密市| 保靖县| 黄浦区| 庆安县| 云林县| 邵武市| 绥宁县| 道孚县| 吉水县| 峨眉山市| 叙永县| 英山县| 郓城县| 昌邑市| 兴化市|