久久亚洲精品天码av,午夜福利屄插穴,午夜福利视频91,亚欧美爽爽爽爽爽,亚洲欧美日韩色色图片,青青操在线观看,精品天堂麻豆av,无码av东京热,婷婷成人亚洲少妇

行業(yè)產(chǎn)品

  • 行業(yè)產(chǎn)品

北京方程嘉鴻科技有限公司


當前位置:北京方程嘉鴻科技有限公司>>細胞因子>>Recombinant Human NOGGIN貨號:120-10細胞因子

Recombinant Human NOGGIN貨號:120-10細胞因子

返回列表頁
參  考  價面議
具體成交價以合同協(xié)議為準

產(chǎn)品型號

品       牌

廠商性質生產(chǎn)商

所  在  地北京市

聯(lián)系方式:王杰查看聯(lián)系方式

更新時間:2016-06-02 01:34:32瀏覽次數(shù):1847次

聯(lián)系我時,請告知來自 制藥網(wǎng)

產(chǎn)品簡介

Recombinant Human NOGGIN貨號:120-10細胞因子
細胞因子(cytokine,CK)是一類能在細胞間傳遞信息、具有免疫調節(jié)和效應功能的蛋白質或小分子多肽。
作用特點:多效性、重疊性、協(xié)同性、拮抗性和雙重性。

詳細介紹

Recombinant Human NOGGIN貨號:120-10細胞因子

 

胞因子受體存在著可溶性形式,掌握可溶性細胞因子受體產(chǎn)生的規(guī)律及其生理和病理意義,必將擴展人們對細胞因子網(wǎng)絡作用的認識。檢測細胞因子及其受體的水平已成為基礎和臨床免疫學研究中的一個重要的方面。Catalog Number:

 
Catalog Number:
120-10C
Description:
Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant human Noggin is a 46 kDa disulfide-linked homodimer (120-10C) consisting of two 206 amino acid polypeptide chains. Monomeric glycosylated Noggin migrates at an apparent molecular weight of approximay 28.0-33.0 kDa by SDS PAGE analysis under reducing conditions.
AA Sequence:
QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC
Source:
HEK293 cells
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
Determined by its ability to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is 2.0-3.0 ng/ml of Noggin.
 
 
 
 
Cross Reactivity:
Chicken, Mouse, Human
Research Interests:
Bone, Skeletal, Cartilage Bone, Skeletal, Cartilage Stem Cells & Differentiation Stem Cells & Differentiation
 
 
Country of Origin:
USA


您感興趣的產(chǎn)品PRODUCTS YOU ARE INTERESTED IN

制藥網(wǎng) 設計制作,未經(jīng)允許翻錄必究 .? ? ? Copyright(C)?2021 http://m.jjhengye.com,All rights reserved.

以上信息由企業(yè)自行提供,信息內容的真實性、準確性和合法性由相關企業(yè)負責,制藥網(wǎng)對此不承擔任何保證責任。 溫馨提示:為規(guī)避購買風險,建議您在購買產(chǎn)品前務必確認供應商資質及產(chǎn)品質量。

會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

請 登錄 后再收藏

提示

您的留言已提交成功!我們將在第一時間回復您~
奎屯市| 丘北县| 扶风县| 乐都县| 灵石县| 永和县| 连山| 齐齐哈尔市| 平潭县| 志丹县| 辛集市| 玉屏| 九寨沟县| 新竹市| 南宁市| 湘阴县| 保定市| 垣曲县| 浦江县| 宝鸡市| 呈贡县| 崇仁县| 长乐市| 开阳县| 榆中县| 宝丰县| 蒙自县| 韶山市| 富宁县| 宜阳县| 永川市| 玉溪市| 滕州市| 花垣县| 伊川县| 刚察县| 偃师市| 寻乌县| 屏东市| 阿图什市| 宜兰县|