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北京華豫清源國際貿(mào)易有限公司
主營產(chǎn)品: 離子交換樹脂,藥用輔料樹脂,固相肽合成樹脂,拋光樹脂,螯合樹脂,混床樹脂,移動床生物膜污水處理,凈水設(shè)備,機(jī)械設(shè)備,貨物及技術(shù)進(jìn)出口 |
![]() |
北京華豫清源國際貿(mào)易有限公司
主營產(chǎn)品: 離子交換樹脂,藥用輔料樹脂,固相肽合成樹脂,拋光樹脂,螯合樹脂,混床樹脂,移動床生物膜污水處理,凈水設(shè)備,機(jī)械設(shè)備,貨物及技術(shù)進(jìn)出口 |
2012-1-6
杜笙藥用輔料入駐北京華豫清源貿(mào)易有限公司,為公司的經(jīng)營范圍又?jǐn)U大了許多。
杜笙樹脂 有4種關(guān)于制藥業(yè)配方的應(yīng)用。
TULSION® resins find a number of applications as Excipients in Pharmaceutical Formulations .
應(yīng)用 / Applications
杜笙樹脂于藥品的應(yīng)用大致可以分為以下4大類別 :
The use in pharmaceutical formulations can be classified under one of the following four categories
<味道包覆劑> – 一些藥物含有苦味 ,可用杜笙交換樹脂來吸收此苦味而相對比較沒苦味。人的口中及胃的酸堿值 (pH)大約是在相同的范圍 ,因此藥品不會在口中溶解而只在胃里溶解。因此,當(dāng)藥經(jīng)過口中時(shí) ,藥品的結(jié)構(gòu)仍處于錯(cuò)化物 ,沒有任何的味道被釋出。不同的樹脂選擇來包含苦味,取決于藥品特性 (請連絡(luò)我們以取得更詳細(xì)資料)。
<Taste Masking Agent> – Certain drugs that have a very bitter taste can be made relatively tasess by adsorbing the drugs on Tulsion Exchange Resins . The pH in the mouth being on the basic side compared to the pH in the stomach , the complex drug will not be released in the mouth but only in the stomach. Since while passing through the mouth the drug remains in the complex form , none or very little taste is imparted. The nature of resin used is dependent upon the type of drug being masked (please contact us for more details).
<藥片溶解劑> - 為了確保一旦藥片攝入,能提供所需的藥物。一樣的藥片劑 ,一樣的迅速溶解是可以達(dá)到的。外用試劑添加到藥片配方,以確保藥片溶解。TULSION®樹脂可被當(dāng)成是藥劑溶解劑。這是由于樹脂會比樹脂處于氫﹑鉀的 “Polacrilin鉀” 樹脂的形式容易膨脹,因而成為在這個(gè)應(yīng)用程序的形式樹脂。
<Tablet Disintegrant> – In order to ensure that once a tablet is ingested , the desired drug is delivered . It is desirable that the tablet disintegrates uniformly and quickly. External agents are added to a tablet formulation to ensure the disintegration. TULSION® resins ca be used as a disintegrating agent. This is due to the fact that the resin will swell than the resin in hydrogen form , Potassium form of the resin “Polacrilin Potassium” is preferred in this applications.
<藥效持續(xù)釋放> -緩釋劑是要確保藥物不斷的 ,慢慢的,但穩(wěn)定的速度被釋放到身體。藥劑從離子交換樹脂釋放是 取決于身體內(nèi)不同液體與藥品及樹脂錯(cuò)化物之間的反應(yīng)來決定。對藥物的釋放速度可通過改變控制粒子的大小,樹脂交聯(lián)的程度及樹脂的化學(xué)性質(zhì)。此種持續(xù)性的釋放藥效配方是可以依照不同的應(yīng)用而量身訂作的。
<Sustained Release> – Sustained release formulations ensure that the drug is released continuously into the body at a slower , but steady rate. The release of durgs from ion exchange resins depends upon a series of ionic reactions between various body fluids and drug – resin complex . The rate of release of drugs can be controlled by varying the particle size , degree of cross-linking and the chemistry of resin. The release profile can almost be tailor made to suit a particular application.
<藥效穩(wěn)定藥物> - 例如藥物,維生素B – 12的存儲時(shí),經(jīng)過一段時(shí)間會慢慢分解。此類藥物的穩(wěn)定可藉由使用TULSION®樹脂來達(dá)成。
<Drug Stabilization> – Drugs for instance, Vitamin B-12 when stored , degenerate after some time. The stabilization of such drugs can be brought about using Tulsion resins.
TULSION®杜笙樹脂 是經(jīng)過美國藥品管理局認(rèn)證通過 ,并具有 ISO 9001 及ISO 14001 的品質(zhì)認(rèn)證。