纈氨霉素 Valinomycin 伊普瑞斯提供

 Grade: for Biochemistry
Regulation / Hazardous:  UN: Class 6.1 - Toxic
Storage condition: Keep at 2-10 degrees C.
Manufacturer: Wako Pure Chemical Industries, Ltd.
Summary
 <Antibiotics/Folate Metabolism related Substances>
Antibiotics are substances that inhibit microbial growth （including viruses） and growth of other cells.
This is a peptidic antibiotic that directly acts on the biological membrane or the artificial phospholipid membrane and increases the cation permeability. It is a neutral ionophore. It has extremely high selectivity of K+. K+ penetrates through the membrane that is originally impermeable, and since the membrane potential decreases, oxidative phosphorylation in mitochondria is inhibited.

Synonym Valinomycin
Potassium Ionophore I
Cyclo（Lac-Val-D-Hiv-D-Val-Lac-Val-D-Hiv-D-Val-Lac-Val-D-Hiv-D-Val-）
Cyclo（L-Val-D-Hylva-D-Val-L-Lac-）3
Cyclo（Lac-Val-D-Hiv-D-Val-Lac-Val-D-Hiv-D-Val-）
Antibiotic N-329 B
NSC 122023
Valinomicin
 CAS NO. 2001-95-8
 Molecular Formula C54H90N6O18
 Molecular Weight 1,111.34
Appearance: White - nearly white, crystalline powder - powder
Purity:  85.0+% （HPLC）
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