| 參考價(jià) | ￥950.00 |
| 規(guī)格 | 25 pcs | 950元 | 10000 件可售 |
產(chǎn)品簡(jiǎn)介
| 產(chǎn)地 | 國(guó)產(chǎn) | 規(guī)格 | 25 pcs |
| 級(jí)別 | 化工級(jí) | 證書 | ISO系列證書 |
Description& Advantages
Endogenous proteins are produced and removed in a balanced state, so their cellular levels are generally stable under stable environmental conditions. However, protein production is greatly halted and degradation is enhanced when cells are studied in vitro. To prevent the degradation of proteins under such conditions, one can utilize a cocktail of small molecule inhibitors to block the action of proteases. Generally, protease inhibitor cocktails are used in cell lysates or tissue extracts to increase protein stability. As the name indicates, the cocktail functions to inhibit proteases that would degrade either phosphorylated or non-phosphorylated protein substrates. MedChemExpress Protease Inhibitor Cocktail (EDTA free, mini-Tablet) is a blend of 5 pan-protease inhibitors for protection of protein integrity.
Publications
•Cell. 2020 Apr 30;181(3):621-636.e22.
•Cell Res. 2021 Mar;31(3):345-361.
•Adv Funct Mater. 2020, 2004886.
•Signal Transduct Target Ther. 2021 Sep 4;6(1):333.
•Sci Immunol. 2022 Feb 4;7(68):eabk2092.
•Sci Adv. 2021 Mar 3;7(10):eabe8591.
•EMBO Mol Med. 2020 Dec 7;e12798.
•EMBO J. 2021 May 19;e106183.
•Theranostics. 2021 Mar 4;11(10):4825-4838.
•Theranostics. 2021 Jan 1;11(2):925-940.
•Theranostics. 2020 Oct 30;10(26):12223-12240.
•Theranostics. 2020 Aug 2;10(21):9830-9842.
•Theranostics. 2020 Jul 11;10(19):8834-8850.
•Cell Mol Immunol. 2021 Mar 11.
•Mol Ther. 2021 Jun 7;S1525-0016(21)00312-9.
•Acta Pharm Sin B. 2021 Jun;11(6):1592-1606.
Storage
Protease Inhibitor Cocktail (EDTA free, mini-Tablet) can be stored at 4°C for 2 years.
Protocol
1. This product can be applied in Western Blot analysis, Co-IP, pull-down, IF, IHC, kinase assay and etc.
2. One mini-Tablet can be added to 10mL extraction medium directly. Alternatively, a stock solution (10X conc. one mini-Tablet in 1mL ddH2O) can be prepared. Vortex briefly to accelerate the dissolution. The stock solution is stable for one week when stored at 4°C, and for at least 4 weeks at -20°C.
注：產(chǎn)品僅用于科研
關(guān)聯(lián)品牌
MCE(MedChemExpress)是科研化學(xué)品和生物活性化合物供應(yīng)商。MCE的產(chǎn)品范圍覆蓋各種抑制劑、化合物庫(kù)、重組蛋白等各類活性分子。我們專注于生物活性化合物，擁有多年的發(fā)展歷程和豐富的行業(yè)經(jīng)驗(yàn)，專業(yè)、高效的企業(yè)理念鑄造了MCE在行業(yè)的地位。我們的研發(fā)團(tuán)隊(duì)擁有眾多的化學(xué)家和生物學(xué)家，從產(chǎn)品的HNMR數(shù)據(jù)解析到生物活性數(shù)據(jù)，從客戶的詢價(jià)到產(chǎn)品的售后服務(wù)，MCE擁有著完善的管理體系，從而保證我們的服務(wù)更加高效、準(zhǔn)確。MCE為醫(yī)藥行業(yè)的發(fā)展注入了新的活力，我們是您研發(fā)工作中值得信賴的伙伴！MCE致力于為客戶提供新穎齊全的高品質(zhì)小分子活性化合物。50,000多種特異...
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