L-Homopropargylglycine,HPG,炔標(biāo)記蛋氨酸
L-Homopropargylglycine
L-Homopropargylglycine (HPG) is an amino acid analog of methionine that contains a very small modification, specifically an alkyne moiety that can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or &lduo;click &rduo; reaction between an azide and an alkyne or cyclooctyne. The alkyne-modified protein is detected with either fluorescent azide or biotin azide. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and patible with downstream LC-MS⁄MS and MALDI MS analysis.
Molecular weight | 163.60 (HCl salt) |
Chemical position | C6H10ClNO2 |
CAS | 98891-36-2 |
Solubility | Water, DMSO, DMF |
Purity | >95% (H NMR) |
Appearance | White crystalline |
Storage conditions | -20C |
Shipping conditions | Ambient temperature |
L-Homopropargylglycine,HPG,炔標(biāo)記蛋氨酸
公司：西安凱新生物科技有限公司
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