Dde Biotin Picolyl Azide,生物素-吡啶-疊氮,點擊生物素衍生物
Dde Biotin Picolyl Azide is a uniue amine reactive, cleavable biotin probe that allows for release of the captured biomolecules from streptavidin under mild conditions. This reagent contains a biotin moiety linked to picolyl azide moety through a spacer arm containing a hydrazine cleavable Dde moiety. Captured biomolecules can be efficiently released, typically >90% with 2% hydrazine in aueous media.
Dde Biotin Picolyl Azide incorporates a copper-chelating motif that dramatically accelerates the Cu(I)-catalyzed azide−alkyne cycloaddition (CuAAC) reaction under conditions relevant to biomolecular labeling. Discovery of azides with an internal Cu(I)-chelating motif greatly enhances the utility of CuAAC reaction for monitoring the dynamic glycan biosynthesis in living organisms, the sensitive detection of metabolically labeled proteins DNAs and RNAs, and for many other application where rate acceleration and reduced cell toxicity are highly desirable.
Molecular weight | 815.98 |
Molecular weight left behind | 220.24 |
Chemical position | C38H57N9O9S |
CAS | N/A |
Solubility | DMSO, DMF, THF, DCM, Chloroform |
Purity | >95% (HPLC) |
Appearance | Oil to amorphous solid |
Storage conditions | -20C |
Shipping conditions | Ambient temperature |
結(jié) 構(gòu) 式：
Dde Biotin Picolyl Azide,生物素-吡啶-疊氮,點擊生物素衍生物
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公司：西安凱新生物科技有限公司
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